Global Cardiovascular Drug Delivery Market 2015 - Technologies, Markets and Companies
DUBLIN, Research and Markets has announced the addition
of Jain PharmaBiotech's new report "Cardiovascular Drug Delivery -
Technologies, Markets and Companies" to their offering.
Drug delivery to the
cardiovascular system is different from delivery to other systems because of
the anatomy and physiology of the vascular system; it supplies blood and
nutrients to all organs of the body. Drugs can be introduced into the vascular
system for systemic effects or targeted to an organ via the regional blood
supply. In addition to the usual formulations of drugs such as controlled
release, devices are used as well. This report starts with an introduction to
molecular cardiology and discusses its relationship to biotechnology and drug
delivery systems.
Role of drug delivery in various cardiovascular disorders such as myocardial
ischemia, hypertension and hypercholesterolemia is discussed. Cardioprotection
is also discussed. Some of the preparations and technologies are also
applicable to peripheral arterial diseases. Controlled release systems are
based on chronopharmacology, which deals with the effects of circadian
biological rhythms on drug actions. A full chapter is devoted to drug-eluting
stents as treatment for restenosis following stenting of coronary arteries.
Fifteen companies are involved in drug-eluting stents.
New cell-based therapeutic strategies are being developed in response to the
shortcomings of available treatments for heart disease. Potential repair by
cell grafting or mobilizing endogenous cells holds particular attraction in
heart disease, where the meager capacity for cardiomyocyte proliferation likely
contributes to the irreversibility of heart failure. Cell therapy approaches
include attempts to reinitiate cardiomyocyte proliferation in the adult,
conversion of fibroblasts to contractile myocytes, conversion of bone marrow
stem cells into cardiomyocytes, and transplantation of myocytes or other cells
into injured myocardium.
Advances in molecular pathophysiology of cardiovascular diseases have brought
gene therapy within the realm of possibility as a novel approach to treatment
of these diseases. It is hoped that gene therapy will be less expensive and
affordable because the techniques involved are simpler than those involved in
cardiac bypass surgery, heart transplantation and stent implantation. Gene
therapy would be a more physiologic approach to deliver vasoprotective
molecules to the site of vascular lesion. Gene therapy is not only a
sophisticated method of drug delivery; it may at time need drug delivery
devices such as catheters for transfer of genes to various parts of the
cardiovascular system.
The cardiovascular drug delivery markets are estimated for the years 2014 to
2024 on the basis of epidemiology and total markets for cardiovascular
therapeutics. The estimates take into consideration the anticipated advances
and availability of various technologies, particularly drug delivery devices in
the future. Markets for drug-eluting stents are calculated separately. Role of
drug delivery in developing cardiovascular markets is defined and unmet needs
in cardiovascular drug delivery technologies are identified.
Selected 82 companies that either develop technologies for drug delivery to the
cardiovascular system or products using these technologies are profiled and 80
collaborations between companies are tabulated. The bibliography includes 200
selected references from recent literature on this topic. The report is
supplemented with 29 tables and 7 figures.
Key Topics Covered:
Executive Summary
1. Cardiovascular Diseases
2. Methods for Drug Delivery to the Cardiovascular System
3. Cell Therapy for Cardiovascular Disorders
4. Gene Therapy for Cardiovascular Disorders
5. Drug-Eluting Stents
6. Markets for Cardiovascular Drug Delivery
7. Companies involved in Cardiovascular Drug Delivery
8. References
For more information visit http://www.researchandmarkets.com/research/hgs483/cardiovascular
Source: Research and Markets
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