Studies Show Eptifibatide Equivalent to Abciximab During PCI for STEMI

By Kim Dalton
Sunday, July 26, 2020

The small molecule glycoprotein IIb/IIIa inhibitor (GPI) eptifibatide is just as safe and effective as the better studied but more expensive abciximab in patients undergoing primary percutaneous coronary intervention (PCI) for ST-segment elevation myocardial infarction (STEMI). The less costly GPI’s noninferiority was confirmed by a small randomized trial as well as a large retrospective study, both of which appear in the August 3, 2010, issue of the Journal of the American College of Cardiology.

Reperfusion Equivalent in Randomized Trial

For the EVA-AMI (Eptifibatide Versus Abciximab in Primary PCI for Acute Myocardial Infarction) trial, researchers led by Uwe Zeymer, MD, of Herzzentrum Ludwigshafen ....



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