TCTMD’s Top 10 Most Popular Stories for June 2026

June is not as busy as May when it comes to medical meetings, although multiple stories from the recent New York Valves 2026 conference feature in the most-read articles from the past month. TAVI news revolving around mid- and long-term durability, treatment of asymptomatic patients, futility, and reimbursement accounts for half of the top spots, with topics like the first cardiovascular-kidney-metabolic (CKM) syndrome guideline, gene-editing therapy, post-PCI antiplatelet choice, and use of vitamin K supplementation to reduce coronary calcification rounding out the list.

1. New 10-Year TAVI Data Generally ‘Reassuring’ But Highlight Challenges

High mortality in elderly patients followed over a decade might complicate the lessons learned compared with SAVR.

2. AHA/ACC Release First Comprehensive Guideline on CKM Syndrome

The condition is a main determinant of CV risk and a major contributor to premature mortality, Chiadi Ndumele says.

3. Gene-Editing Therapy Safely Lowers PCSK9, LDL Cholesterol in Phase I: Heart-2

Though there’s still a long way to go before a clinical application of VERVE-102, early results are “super exciting,” one expert says.

4. Meta-analysis: Prasugrel the Best P2Y12 Inhibitor After PCI?

Compared with clopidogrel, the drug comes with better efficacy and less risk of major bleeding than ticagrelor.

5. NY Valves 2026 EARLY TAVR: 5-Year Data Still Support TAVI Over Surveillance in Asymptomatic AS

While the dataset is incomplete, the death and stroke curves appear to separate at 2 years, notes Philippe Généreux.

6. NY Valves 2026 RCT, Real-World Data Show TAVI Durability Up to 7 Years in Low-risk Patients

The results were framed as reassuring, although experts made it clear that longer-term follow-up is needed.

7. Following Successful TAVI, 4% Die between 1 and 12 months: TRITAVI

The data should help with conversations around patient selection and futility, researchers say.

8. NY Valves 2026 What’s Going to Be Hot at New York Valves 2026

Attendees will find 30 late-breaking clinical science and innovation presentations, the LAAC Summit, puppies, and more.

9. Vitamin K Supplementation May Reduce Coronary Calcification: VitaK-CAC

But some argue that without knowledge of what the changes in CAC mean, these supplements are not ready for routine use.

10. CMS Proposes Expanding TAVI Coverage to Asymptomatic Patients

The proposed decision memo also paves the way for triaging by chart review and enhancing flexibility for heart team decisions.

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Beyond the news, several podcasts and videos went live during June, including a new Heart Sounds highlighting what stories the TCTMD journalists have been working on and the latest installment of Hearts & Minds, in which Margaret McEntegart talks with host Yael L. Maxwell about her journey across continents, career pinnacles, and manifestation and visualization practices.

Stay tuned for our coverage of the 2026 Society of Cardiovascular Computed Tomography (SCCT) meeting, which gets started next week in San Diego, CA. And as always, feel free to reach out with any ideas, questions, or feedback.