Is physiologic guidance the solution to residual ischemia? A closer look at DEFINE-PCI



Chapter 1: Background of Physiologic Assessment Post-PCI






Chapter 1: Background
Chapter 2: Results
Chapter 3: Case Examples
Chapter 4: Implications


Listen to physician experts as they discuss the results of DEFINE PCI.

  • The DEFINE PCI study of 467 patients with angiographically successful PCI found that 24% left the cath lab with residual ischemia.
  • Of the patients with residual ischemia, 81.6% of these were caused by an untreated focal stenosis (that was angiographically inapparent) that could potentially be further optimized by additional PCI.
  • What does this mean for physiologic guidance as a planning tool?

Learn more about physiologic guidance.




Gregg Stone

Gregg Stone, MD
Professor of Medicine, Director of Cardiovascular Research and Education  
Cardiovascular Research Foundation
New York, NY



Allen Jeremias, MD
Director of Interventional Cardiology Research
Associate Director, Cardiac Cath Lab
St. Francis Hospital
Roslyn, NY

Habib Samady, MD
Professor of Medicine, Cardiology
Director, Cardiac Cath Lab
Emory University Hospital
Atlanta, GA

Manesh Patel, MD
Professor of Medicine
Chief, Division of Cardiology
Duke University
Durham, NC




Sponsored by: Philips