New Research Shows Abbott's High Sensitive Troponin Test First To Measure Impact Of Mental Stress On The Heart


ABBOTT PARK, Ill., The stresses of life have long been thought to increase a person's risk of heart disease.
But the question remains how to measure the impact of different types of stress on the heart. Now, new research conducted atEmory University shows that Abbott's ARCHITECT STAT High Sensitive Troponin-I (hsTnl) test may detect whether stress –mental and physical – leads to an inadequate oxygen supply to the heart among people with coronary artery disease.

Results from clinical trial data presented at the American College of Cardiology 65th Annual Scientific Session show that patients developing stress-induced ischemia (inadequate oxygen flow to the heart) are likely to have high levels of troponin, a protein that at increased levels can indicate injury to the heart.  Over time, if there is a mismatch in oxygen flow to the heart, there is the potential to damage the muscle and lead to serious health issues, such as heart attack, heart failure or even death.4  High sensitive troponin tests, including Abbott's ARCHITECT STAT High Sensitive Troponin-I (hsTnI) test used in this study, are commercially available outside of the United States and in development in the United States.

"We've always believed that stress can be harmful to cardiac health. We now show that this harm is also reflected by elevated levels of circulating troponin," says lead study author Dr. Arshed A. Quyyumi, M.D., professor of medicine, Division of Cardiology at Emory University School of Medicine, and co-director of the Emory Clinical Cardiovascular Research Institute. "With this study, for the first time doctors have a way to measure the impact of ischemia with a high sensitive troponin test. Because we and others have shown that a higher circulating level of troponin is associated with worse long-term outcomes, such as heart attack or even death, doctors may eventually use this information to prevent serious complications from developing."

Source: Abbott

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