Company Will Also Introduce Its Design of a Fully Drug Eluting Bioabsorbable Scaffold with Endothelial Progenitor Cell (EPC) Capture Technology

HONG KONG, OrbusNeich today announced that multiple presentations of clinical data for the COMBO Dual Therapy Stent will take place next week at TCT 2012 in Miami Beach.

The scientific sessions will feature cumulative results from the REMEDEE study (Randomized Evaluation of an abluMinal sirolimus coatED bio-Engineered stEnt), a randomized trial of the COMBO Dual Therapy Stent versus a drug eluting stent, and data from the REMEDEE OCT and EGO COMBO studies to assess the healing profile of COMBO compared to a drug eluting stent by optical coherence tomography (OCT). Michael Haude, M.D., of Medical Clinic I at the Lukaskrankenhaus in Neuss, Germany, will deliver the oral presentation “REMEDEE Combo (OrbusNeich) Program Update” during the session “Metallic Drug-Eluting Stents with Bioabsorbable Polymers” at 2:37 p.m. EDT on Tuesday, Oct. 23, in Hall A/Coronary Theater at the Miami Beach Convention Center.

In addition, posters featuring the COMBO Dual Therapy Stent will be displayed from 8 a.m. to 10 a.m. EDT on Tuesday, Oct. 23, in Hall D. The principal investigators will be available during that time to answer physicians’ questions. Specifically, the posters will be:

• “The REMEDEE OCT Study: A Prospective Randomized Study of the Early Vascular Healing of a Novel Dual Therapy Stent in Comparison with an Everolimus-Eluting Stent,” (TCT-282), presented by Ulf Landmesser, M.D., Ph.D., of the Cardiovascular Center, University Hospital of Zürich, Switzerland
• “Evaluation of Neointimal Healing and Late Luminal Loss of Endothelial Progenitor Cell Capturing Sirolimus-Eluting (COMBO) Stent by Optical Coherence Tomography: The EGO-COMBO Study,” (TCT-292), presented by Stephen W.L. Lee, M.D., of the Queen Mary Hospital, University of Hong Kong, China

At 7 a.m. EDT on Thursday, Oct. 25, in room C223-224, a breakfast symposium entitled “OrbusNeich’s COMBO Dual Therapy Stent: Addressing the Limitations of Drug Eluting Stents” will be chaired by Prof. Lee and Roxana Mehran, M.D., of Mount Sinai Medical Center, New York. Dr. Mehran will open the symposium with a discussion of the challenge facing today’s practicing cardiologist – balancing bleeding and ischemic events. Prof. Haude will present results from the REMEDEE study, while Jonathan M. Hill, M.D., of the King's College Hospital, London, will discuss modes of assessing the effect of EPC capture on vascular healing. Prof. Lee will then discuss results from the EGO COMBO study, and Dr. Landmesser will present the study design and preliminary results of REMEDEE OCT.

Also at TCT 2012, Robert Cottone, OrbusNeich’s vice president of intellectual property & technologies, will present “Design of a Fully Drug-Eluting Bioabsorbable Scaffold with EPC-Capture Technology” at 5:52 p.m. EDT on Tuesday, Oct. 23, in Hall A/Coronary Theater during the session “Bioresorbable Vascular Scaffolds: Latest Designs and Clinical Study Evidence.”

Source: OrbusNeich