First Optical Coherence Tomography Case Report of a Patient Requiring Urgent Surgery Two Weeks After Revascularization Published in the Journal of Invasive Cardiology

HONG KONG,  OrbusNeich today announced that optical coherence tomography (OCT) results published in the April edition of the Journal of Invasive Cardiology show that the Genous Stent achieves full strut coverage and endothelialization two weeks after percutaneous coronary intervention (PCI). The case report features OCT images of a patient who underwent PCI in advance of a non-deferrable surgery for stomach cancer and who safely discontinued dual antiplatelet therapy (DAPT) at two weeks following revascularization.

The patient, a 78-year old male with chest pain due to an unstable angina, was diagnosed with a tight stenosis in the mid-left anterior descending (LAD) coronary artery during the preoperative assessment. A plain old balloon angioplasty (POBA) procedure resulted in residual restenosis that required the implantation of a stent. At two-week angiographic follow-up, no in-stent restenosis was observed and OCT showed excellent coverage of the stent struts. Two small aneurysms were observed behind the stent struts that were most likely the result of dissection during the initial POBA procedure. A second OCT performed at four weeks showed that the first aneurysm had completely disappeared and the second had decreased in size.

“By confirming the rapid strut coverage achieved by Genous with OCT, we were able to confidently prescribe the discontinuation of DAPT for this patient at two weeks,” said Jin-Man Cho, M.D., of the Division of Cardiology, Kyung-Hee University at Gangdong, Seoul, Korea. “The Genous Stent may provide an excellent option for patients who require non-deferrable, non-cardiac surgery and for whom early discontinuation of DAPT is required. Previously published studies have also shown that the Genous Stent is safe and associated with low rates of stent thrombosis when accompanied by only two weeks of DAPT.”

Source: OrbusNeich