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Presentation TCT 2025

Smarter Trial Design: Using AI and Real-World Data for Protocol Modeling and Trial Feasibility

Presenter: Harun Kundi

October 27, 2025

Presentation TCT 2025

Commentary

Presenter: Michael J. Reardon

October 27, 2025

Presentation TCT 2025

Percutaneous Transseptal Transcatheter Mitral Valve Replacement using a Dedicated Balloon Expandable Valve: 1 Year Outcomes from the ENCIRCLE Trial using the SAPIEN M3

Presenter: David Daniels

October 27, 2025

Presentation TCT 2025

Commentary

Presenter: Tsuyoshi Kaneko

October 27, 2025

Presentation TCT 2025

Non-Inferiority Trials – Bridge or Barrier to Patient-Centered Progress?

Presenter: Sanjay Kaul

October 27, 2025

Presentation TCT 2025

Tendyne Transcatheter Mitral Valve System in Patients with Severe Mitral Annular Calcification: One-year Outcomes from the SUMMIT Severe MAC Cohort

Presenter: Paul Sorajja

October 27, 2025

Presentation TCT 2025

Subgroup Analyses in Non-Inferiority Studies: Signal or Noise?

Presenter: Björn Redfors

October 27, 2025

Presentation TCT 2025

Commentary

Presenter: Stefan Blankenberg

October 27, 2025

Presentation TCT 2025

How to Interpret a “Negative” Non-Inferiority Trial: Case-Based Discussion

Presenter: Donald Cutlip

October 27, 2025

Presentation TCT 2025

Long-Term Follow-up of the PARTNER 3 Low-Risk Randomized Trial: Seven-Year Clinical and Echocardiographic Outcomes

Presenter: Michael J. Mack

October 27, 2025

Presentation TCT 2025

Sequential Superiority After Non-Inferiority: Opportunities and Risks

Presenter: Roseann M. White

October 27, 2025

Presentation TCT 2025

Commentary

Presenter: Bernard Prendergast

October 27, 2025

Presentation TCT 2025

How to Design (and How Not to Design) a Non-Inferiority Trial

Presenter: Kevin Bainey

October 27, 2025

Presentation TCT 2025

Defining the Prevalence of Valvular Heart Disease in Older Americans: The PREVUE-VALVE Study

Presenter: David J. Cohen

October 27, 2025

Presentation TCT 2025

Real-World Data from Data Aggregators: Opportunities and Challenges

Presenter: Ryan Ahern

October 27, 2025

Presentation TCT 2025

Hybrid Trial Designs and Real-World Evidence: Will They Ever Be Prime Time?

Presenter: Robert W. Yeh

October 27, 2025

Presentation TCT 2025

Rational Dispersion of Novel Technologies & the Need for Additional Evidence Generation: Lessons Learned from Recent CMS NCDs

Presenter: Sreekanth Vemulapalli

October 27, 2025

Presentation TCT 2025

Linkage of Clinical Trial Evidence with Administrative Claims: Pros and Cons

Presenter: Eric A. Secemsky

October 27, 2025

Presentation TCT 2025

Swimming with the SHARCs: Advancing Harmonization of Definitions Used in Clinical Trials of Cardiogenic Shock

Presenter: Mitchell W. Krucoff

October 27, 2025

Presentation TCT 2025

Lessons Learned from 800+ Patients Treated with Tricuspid TEER: Update from the TRILUMINATE Pivotal Trial

Presenter: Jonathan G. Schwartz

October 26, 2025

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Smarter Trial Design: Using AI and Real-World Data for Protocol Modeling and Trial Feasibility

Commentary

Percutaneous Transseptal Transcatheter Mitral Valve Replacement using a Dedicated Balloon Expandable Valve: 1 Year Outcomes from the ENCIRCLE Trial using the SAPIEN M3

Commentary

Non-Inferiority Trials – Bridge or Barrier to Patient-Centered Progress?

Tendyne Transcatheter Mitral Valve System in Patients with Severe Mitral Annular Calcification: One-year Outcomes from the SUMMIT Severe MAC Cohort

Subgroup Analyses in Non-Inferiority Studies: Signal or Noise?

Commentary

How to Interpret a “Negative” Non-Inferiority Trial: Case-Based Discussion

Long-Term Follow-up of the PARTNER 3 Low-Risk Randomized Trial: Seven-Year Clinical and Echocardiographic Outcomes

Sequential Superiority After Non-Inferiority: Opportunities and Risks

Commentary

How to Design (and How Not to Design) a Non-Inferiority Trial

Defining the Prevalence of Valvular Heart Disease in Older Americans: The PREVUE-VALVE Study

Real-World Data from Data Aggregators: Opportunities and Challenges

Hybrid Trial Designs and Real-World Evidence: Will They Ever Be Prime Time?

Rational Dispersion of Novel Technologies & the Need for Additional Evidence Generation: Lessons Learned from Recent CMS NCDs

Linkage of Clinical Trial Evidence with Administrative Claims: Pros and Cons

Swimming with the SHARCs: Advancing Harmonization of Definitions Used in Clinical Trials of Cardiogenic Shock

Lessons Learned from 800+ Patients Treated with Tricuspid TEER: Update from the TRILUMINATE Pivotal Trial

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