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Presentation TCT 2016

Analyzing Repeat Events

Presenter: Scott Berry, Stuart J. Pocock, Eugene H. Blackstone

October 30, 2016

Presentation TCT 2016

Limitations of Composite Endpoints and Strategies for Hierarchical Testing

Presenter: Scott Berry, Stuart J. Pocock, Jan G. P. Tijssen

October 30, 2016

Presentation TCT 2016

Moderate Aortic Stenosis + Heart Failure: Introduction to the UNLOAD Trial

Presenter: A. Pieter Kappetein, Allan Schwartz, Martin B. Leon

October 30, 2016

Presentation TCT 2016

Strengths and Limitations of Meta-analysis: Standard, Network and Bayesian Techniques, and the Value of Individual Patient-level Data Pooling

Presenter: Ori Ben-Yehuda, Tullio Palmerini, Giuseppe Biondi-Zoccai

October 30, 2016

Presentation TCT 2016

TMVR Clinical Trial Design: Early Insights from Industry

Presenter: Charles J. Davidson, Nicole Ibrahim, Dan Mans

October 30, 2016

Presentation TCT 2016

TMVR Clinical Trial Design: Similarities and Differences -TAVR and Transcatheter Mitral Therapy Clinical Trials

Presenter: Charles J. Davidson, Nicole Ibrahim, Paul Sorajja

October 30, 2016

Presentation TCT 2016

When Are Randomized Trials Not Enough, and Can Observational Data Reliably Inform Comparative Effectiveness Decisions?

Presenter: Eugene H. Blackstone, Robert W. Yeh, Robert A. Harrington

October 30, 2016

Presentation TCT 2016

Can Propensity and Instrumental Variable Methods Overcome the Limitations of Observational Databases: Lessons From TRANSLATE-ACS

Presenter: Eugene H. Blackstone, Robert W. Yeh, Tracy Y. Wang

October 30, 2016

Presentation TCT 2016

Why are These Trials Recruiting Slowly and How Can We Improve Recruitment Rates?

Presenter: Farrell O. Mendelsohn, Stephen G. Worthley, Martin B. Leon

October 30, 2016

Presentation TCT 2016

FDA Perspectives

Presenter: Charles J. Davidson, Nicole Ibrahim, John C Laschinger

October 30, 2016

Presentation TCT 2016

Comparison of Propensity Score Methods and Covariate Adjustment in Observational Studies: Similarities and Differences

Presenter: Eugene H. Blackstone, Robert W. Yeh, Stuart J. Pocock

October 30, 2016

Presentation TCT 2016

Alcohol Chemical Neurolysis (Ablative Solutions): Peregrine Results and the Sham-controlled TARGET BP I Trial

Presenter: Farrell O. Mendelsohn, Stephen G. Worthley, David E. Kandzari

October 30, 2016

Presentation TCT 2016

Importance of Unmeasured Confounders in Observational Registries: ASCERT and Other Examples

Presenter: Eugene H. Blackstone, Robert W. Yeh, Kirk N. Garratt

October 30, 2016

Presentation TCT 2016

Device Overview and Ongoing Study Design: Kona WAVE IV Trial

Presenter: Farrell O. Mendelsohn, Stephen G. Worthley, Roland E Schmieder

October 30, 2016

Presentation TCT 2016

The Smoker's Paradox Revisited: A Five-Year Patient-Level Pooled Analysis of 17 Randomized Controlled Trials

Presenter: Mayank Yadav

October 30, 2016

Presentation TCT 2016

Meta-analysis and Synthesis of Watchman Trials: Relative Safety and Efficacy vs Warfarin and NOACs in Anticoagulant Indicated Patients (Including Cost-effectiveness)

Presenter: Vivek Y. Reddy, Steven J. Yakubov

October 30, 2016

Presentation TCT 2016

Value and Hazards of Subgroup Analysis: the SYNTAX to EXCEL Case Study

Presenter: Peter Juni, E. Magnus Ohman, Ori Ben-Yehuda

October 30, 2016

Presentation TCT 2016

Clinical Trial Interpretation: Relative vs Absolute Differences

Presenter: Peter Juni, E. Magnus Ohman, John A. Bittl

October 30, 2016

Presentation TCT 2016

Device Overview and Ongoing Study Design: Medtronic GLOBAL SYMPLICITY SPYRAL HTN Trial Program

Presenter: Farrell O. Mendelsohn, Stephen G. Worthley, David E. Kandzari

October 30, 2016

Presentation TCT 2016

The Last Word on DES in Diabetics: Two-Year TUXEDO Outcomes

Presenter: Dean J. Kereiakes, Pieter C. Smits, Upendra Kaul

October 30, 2016

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Analyzing Repeat Events

Limitations of Composite Endpoints and Strategies for Hierarchical Testing

Moderate Aortic Stenosis + Heart Failure: Introduction to the UNLOAD Trial

Strengths and Limitations of Meta-analysis: Standard, Network and Bayesian Techniques, and the Value of Individual Patient-level Data Pooling

TMVR Clinical Trial Design: Early Insights from Industry

TMVR Clinical Trial Design: Similarities and Differences -TAVR and Transcatheter Mitral Therapy Clinical Trials

When Are Randomized Trials Not Enough, and Can Observational Data Reliably Inform Comparative Effectiveness Decisions?

Can Propensity and Instrumental Variable Methods Overcome the Limitations of Observational Databases: Lessons From TRANSLATE-ACS

Why are These Trials Recruiting Slowly and How Can We Improve Recruitment Rates?

FDA Perspectives

Comparison of Propensity Score Methods and Covariate Adjustment in Observational Studies: Similarities and Differences

Alcohol Chemical Neurolysis (Ablative Solutions): Peregrine Results and the Sham-controlled TARGET BP I Trial

Importance of Unmeasured Confounders in Observational Registries: ASCERT and Other Examples

Device Overview and Ongoing Study Design: Kona WAVE IV Trial

The Smoker's Paradox Revisited: A Five-Year Patient-Level Pooled Analysis of 17 Randomized Controlled Trials

Meta-analysis and Synthesis of Watchman Trials: Relative Safety and Efficacy vs Warfarin and NOACs in Anticoagulant Indicated Patients (Including Cost-effectiveness)

Value and Hazards of Subgroup Analysis: the SYNTAX to EXCEL Case Study

Clinical Trial Interpretation: Relative vs Absolute Differences

Device Overview and Ongoing Study Design: Medtronic GLOBAL SYMPLICITY SPYRAL HTN Trial Program

The Last Word on DES in Diabetics: Two-Year TUXEDO Outcomes

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