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Presentation TCT 2025

Placebo-Controlled Interventional Trials: A Sham No More

Presenter: Rasha Al-Lamee

October 27, 2025

Presentation TCT 2025

Spoiler Alert: Crossovers (Treatment Switches) can Negate the Trial Efficacy: Insights from The Ischemia Trial

Presenter: John Gregson

October 27, 2025

Presentation TCT 2025

The Core of Clinical Event Adjudication: Where is CEC Now and Where Do They Go Next?

Presenter: Marc P. Bonaca

October 27, 2025

Presentation TCT 2025

Can Adaptive and Single-Arm Studies Meet the Needs of Key Stakeholders?

Presenter: Rasha Al-Lamee

October 27, 2025

Presentation TCT 2025

Case-Based Discussion: Designing a Contemporary Cardiovascular Trial

Presenter: Stephan Windecker

October 27, 2025

Presentation TCT 2025

Modifying the Win Ratio for Noninferiority Trials: A Bridge Too Far?

Presenter: Björn Redfors

October 27, 2025

Presentation TCT 2025

Is the WIN ratio always a “Winner”: Where It’s Useful, Where It’s Not

Presenter: John Gregson

October 27, 2025

Presentation TCT 2025

Adaptive and Sequential Designs: From Concept to Execution

Presenter: Graeme L. Hickey

October 27, 2025

Presentation TCT 2025

Non-Inferiority Trials – Bridge or Barrier to Patient-Centered Progress?

Presenter: Sanjay Kaul

October 27, 2025

Presentation TCT 2025

Subgroup Analyses in Non-Inferiority Studies: Signal or Noise?

Presenter: Björn Redfors

October 27, 2025

Presentation TCT 2025

How to Interpret a “Negative” Non-Inferiority Trial: Case-Based Discussion

Presenter: Donald Cutlip

October 27, 2025

Presentation TCT 2025

Sequential Superiority After Non-Inferiority: Opportunities and Risks

Presenter: Roseann M. White

October 27, 2025

Presentation TCT 2025

How to Design (and How Not to Design) a Non-Inferiority Trial

Presenter: Kevin Bainey

October 27, 2025

Presentation TCT 2025

Real-World Data from Data Aggregators: Opportunities and Challenges

Presenter: Ryan Ahern

October 27, 2025

Presentation TCT 2025

Hybrid Trial Designs and Real-World Evidence: Will They Ever Be Prime Time?

Presenter: Robert W. Yeh

October 27, 2025

Presentation TCT 2025

Rational Dispersion of Novel Technologies & the Need for Additional Evidence Generation: Lessons Learned from Recent CMS NCDs

Presenter: Sreekanth Vemulapalli

October 27, 2025

Presentation TCT 2025

Linkage of Clinical Trial Evidence with Administrative Claims: Pros and Cons

Presenter: Eric A. Secemsky

October 27, 2025

Presentation TCT 2025

Coordinating ARC Event Definition in Cardiogenic Shock: pVAD, MCS, Adult ECMO, and Beyond

Presenter: Jeffrey Popma

October 27, 2025

Presentation TCT 2025

Swimming with the SHARCs: Advancing Harmonization of Definitions Used in Clinical Trials of Cardiogenic Shock

Presenter: Mitchell W. Krucoff

October 27, 2025

Presentation TCT 2025

Cardiogenic Shock Working Group SCAI Definitions and Phenotypes: Why we Need Both

Presenter: Navin K. Kapur

October 27, 2025

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Placebo-Controlled Interventional Trials: A Sham No More

Spoiler Alert: Crossovers (Treatment Switches) can Negate the Trial Efficacy: Insights from The Ischemia Trial

The Core of Clinical Event Adjudication: Where is CEC Now and Where Do They Go Next?

Can Adaptive and Single-Arm Studies Meet the Needs of Key Stakeholders?

Case-Based Discussion: Designing a Contemporary Cardiovascular Trial

Modifying the Win Ratio for Noninferiority Trials: A Bridge Too Far?

Is the WIN ratio always a “Winner”: Where It’s Useful, Where It’s Not

Adaptive and Sequential Designs: From Concept to Execution

Non-Inferiority Trials – Bridge or Barrier to Patient-Centered Progress?

Subgroup Analyses in Non-Inferiority Studies: Signal or Noise?

How to Interpret a “Negative” Non-Inferiority Trial: Case-Based Discussion

Sequential Superiority After Non-Inferiority: Opportunities and Risks

How to Design (and How Not to Design) a Non-Inferiority Trial

Real-World Data from Data Aggregators: Opportunities and Challenges

Hybrid Trial Designs and Real-World Evidence: Will They Ever Be Prime Time?

Rational Dispersion of Novel Technologies & the Need for Additional Evidence Generation: Lessons Learned from Recent CMS NCDs

Linkage of Clinical Trial Evidence with Administrative Claims: Pros and Cons

Coordinating ARC Event Definition in Cardiogenic Shock: pVAD, MCS, Adult ECMO, and Beyond

Swimming with the SHARCs: Advancing Harmonization of Definitions Used in Clinical Trials of Cardiogenic Shock

Cardiogenic Shock Working Group SCAI Definitions and Phenotypes: Why we Need Both

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