Byeong-Keuk Kim and C. Michael Gibson discuss a randomized trial of ticagrelor monotherapy versus ticagrelor with aspirin in STEMI.

Georgios Vlachojannis and C. Michael Gibson discuss a randomized trial of prehospital crushed versus uncrushed prasugrel in STEMI.

Deepak Bhatt and C. Michael Gibson discuss data on sotagliflozin in diabetes.

Jeffrey Moses and C. Michael Gibson discuss a randomized trial of cerebral embolic protection during TAVR.

Salim Yusuf and C. Michael Gibson discuss aspirin alone and in combination with a polypill for CVD primary prevention.

Philipp Lurz and C. Michael Gibson discuss a randomized trial of ASD closure after TMVr.

Roxana Mehran and C. Michael Gibson discuss 3-month and 1-month DAPT after everolimus-eluting stents in high-bleeding-risk patients.

Steven Steinhubl and C. Michael Gibson discuss 3-year outcomes in a nationwide, randomized, pragmatic clinical trial of A-fib screening.

Damien Collison and C. Michael Gibson discuss a randomized trial of physiology-guided PCI optimization.

A. Michael Lincoff and C. Michael Gibson discuss CV outcomes with omega-3 carboxylic acids in patients with high vascular risk and atherogenic dyslipidemia.