TCTMD’s Top 10 Most Popular Stories for September 2019
A range of topics from the ESC Congress 2019 dominated the top stories in September, with two TCT 2019 trials making the list.
DAPA-HF’s big win for dapagliflozin in heart failure patients, both with and without diabetes, led the top 10 list this month. The TWILIGHT trial from TCT 2019 also made the top three, along with new European Society of Cardiology (ESC) guidelines for the freshly coined concept of “chronic coronary syndromes.” In fact, all but two of the most-clicked stories on TCTMD this month came from the ESC Congress, covering everything from CV risk-factor exposure to antiplatelet choices in ACS, 2-year MITRA-FR numbers, and the COMPLETE trial results for culprit versus complete revascularization in STEMI.
Investigators saw benefits with the SGLT2 inhibitor across all subgroups. One observer predicts a new era of heart failure care.
“You may have stable phases and less stable phases,” says one writing group chair. But the disease is, in most cases, progressing.
Experts agree the findings suggest that aspirin can be dropped in practice 3 months after PCI in this high-risk patient cohort.
Even small reductions in LDL and BP along with lifestyle and diet changes can have a positive effect on cardiovascular health.
Investigators actually designed the trial expecting to demonstrate superiority for ticagrelor. Things didn’t go as planned.
Two-year data allow for more direct comparison with the COAPT results, and a post hoc analysis offers a “surprise.”
The results justify waiting to completely revascularize if a complex patient presents in the middle of the night, an expert says.
The full results contain a “glimmer of hope” that sacubitril/valsartan will be an option for some HFpEF patients.
While the study adds needed data, it does not fully answer the question of whether 1-month therapy strikes the perfect balance.
This latest study “closes the loop” in a series of trials testing the NOACs in this setting and is the first not to get a win for bleeding.
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SEE ALSO: Our top blog post of September 2019, by Off Script blogger Quinn Capers IV, MD.
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