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Antithrombotic therapy does not provide a benefit for clinically stable but symptomatic outpatients with COVID-19, published results of the ACTIV-4b trial affirm. Neither aspirin nor apixaban (Eliquis; Bristol Myers Squibb) at prophylactic or therapeutic doses reduced what were already very low rates of major adverse cardiopulmonary outcomes versus placebo, and both modestly increased bleeding, researchers led by Jean Connors, MD (Brigham and Women’s Hospital, Boston, MA), report in a paper published online

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ACTIV-4b: No Antithrombotic Therapy Needed for COVID-19 Outpatients

October 13, 2021

Rivaroxaban Again Linked to More Bleeding vs Other DOACs

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Rivaroxaban Again Linked to More Bleeding vs Other DOACs

October 11, 2021

Could an App Replace Statin Prescribing by Doctors?

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Could an App Replace Statin Prescribing by Doctors?

Michael O'Riordan

September 08, 2021

Fixed-Dose Combo Therapy Slashes CVD Risk in Primary Prevention

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Fixed-Dose Combo Therapy Slashes CVD Risk in Primary Prevention

Michael O'Riordan

August 31, 2021

Milrinone, Dobutamine Comparable for Cardiogenic Shock: DOREMI

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Milrinone, Dobutamine Comparable for Cardiogenic Shock: DOREMI

August 10, 2021

STROKE-VT: DOACs Cut Cerebrovascular Events After LV Arrhythmia Ablation

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STROKE-VT: DOACs Cut Cerebrovascular Events After LV Arrhythmia Ablation

July 29, 2021

Apixaban May Be Best DOAC for Frail, Older Patients With AF

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Apixaban May Be Best DOAC for Frail, Older Patients With AF

July 19, 2021

Latest Statin Risk-Benefit Analysis: More Harm Than Good?

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Latest Statin Risk-Benefit Analysis: More Harm Than Good?

Yael L. Maxwell

July 15, 2021

DOACs May Have Advantage Over VKAs After TAVI, Study Hints

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DOACs May Have Advantage Over VKAs After TAVI, Study Hints

July 14, 2021

ACTION: Full-Dose Rivaroxaban Doesn’t Help in Hospitalized COVID-19

News Conference News ACC 2021

ACTION: Full-Dose Rivaroxaban Doesn’t Help in Hospitalized COVID-19

May 17, 2021

Clopidogrel, Not Aspirin, for Post-DAPT Monotherapy After PCI: HOST-EXAM

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Clopidogrel, Not Aspirin, for Post-DAPT Monotherapy After PCI: HOST-EXAM

May 16, 2021

New VARC-3 Definitions Provide a Road Map for Future Aortic Valve Research

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New VARC-3 Definitions Provide a Road Map for Future Aortic Valve Research

Michael O'Riordan

April 23, 2021

Pills for Erectile Dysfunction Linked to Fewer CVD Deaths

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Pills for Erectile Dysfunction Linked to Fewer CVD Deaths

March 24, 2021

Too Easy to Misconstrue: Is It Time to Ditch Periprocedural MI?

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Too Easy to Misconstrue: Is It Time to Ditch Periprocedural MI?

Michael O'Riordan

December 02, 2020

TCTMD’s Top 10 Most Popular Stories for September 2020

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TCTMD’s Top 10 Most Popular Stories for September 2020

October 01, 2020

THALES: Ticagrelor Plus Aspirin Cuts Repeat Events After Stroke, TIA

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THALES: Ticagrelor Plus Aspirin Cuts Repeat Events After Stroke, TIA

July 16, 2020

Inclisiran Data in NEJM Prompt Talk of What Comes Next

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Inclisiran Data in NEJM Prompt Talk of What Comes Next

March 24, 2020

Snapshot of Revascularization Outcomes Offers Some Reassurances, Some Surprises

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Snapshot of Revascularization Outcomes Offers Some Reassurances, Some Surprises

February 14, 2020

TCTMD’s Top 10 Most Popular Stories for September 2019

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TCTMD’s Top 10 Most Popular Stories for September 2019

October 01, 2019

Off Script: A (Not So) Brief History of Aspirin’s Rise and Fall

News Opinion Off Script TCT 2019

Off Script: The TWILIGHT of Aspirin? A Brief History of ASA’s Rise and Fall

September 29, 2019

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